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What and how is it used?
(naloxone) is an opioid antagonist used for the complete or partial reversal of opioid overdose, including respirators is also used for diagnosis of suspected or known acute opioid overdose and also for blood pressure support in septic shock. is available in generic form.
What are side effect
shortness of breath, or
Severe side effects include:
high or low blood pressure,
shortness of breath,
abnormal brain function (encephalopathy),
NARCAN (naloxone hydrochloride injection, USP), an opioid antagonist, is a synthetic congener of oxy.
NARCAN® (Naloxone Hydrochloride) Structural Formula Illustration
Naloxone hydrochloride occurs as a white to slightly off-white powder, and is soluble in water, in dilute acids, and in strong alkali; slightly soluble in alcohol; practically insoluble in ether and in chloroform.
NARCAN (naloxone) injection is available as a sterile solution for intravenous, intramuscular and subcutaneous administration in three concentrations: 0.02 mg, 0.4 mg and 1 mg of naloxone hydrochloride per mL. pH is adjusted to 3.5 ± 0.5 with hydrochloric acid.
The 0.02 mg/mL strength is an unpreserved, paraben-free formulation containing 9 mg/mL sodium chloride.
The 0.4 mg/mL vial contains 8.6 mg/mL of sodium chloride and 2 mg/mL of methylparaben and propylparaben as preservatives in a ratio of 9:1. The 0.4 mg/mL ampul is also available in an unpreserved, paraben-free formulation containing 9 mg/mL of sodium chloride.
The 1 mg/mL vial contains 8.35 mg/mL of sodium chloride and 2 mg/mL of methylparaben and propylparaben as preservatives in a ratio of 9:1. The 1 mg/mL ampul is also available in an unpreserved, paraben-free formulation containing 9 mg/mL of sodium chloride.